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RESEARCH PRODUCT

Enduring Changes in Decision Making in Patients with Full Remission from Anorexia Nervosa

Jose A Fernández-formosoFernando Fernández-arandaFernando Fernández-arandaFernando Fernández-arandaRosa M. BañosRosa M. BañosGema FrühbeckGema FrühbeckIsabel SánchezIsabel SánchezZaida AgüeraZaida AgüeraAna B CrujeirasTrevor StewardTrevor StewardNadine RiescoNadine RiescoCristina BotellaJosé Manuel Fernández-realSusana Jiménez-murciaSusana Jiménez-murciaSusana Jiménez-murciaAmaia RodríguezAmaia RodríguezVirginia Martín-romeraIris Tolosa-solaFelipe F. CasanuevaFrancisco J. TinahonesFrancisco J. OrtegaJosé Carlos Fernández-garcíaRoser GraneroRoser GraneroRafael De La TorreRafael De La TorreJosé M. MenchónJosé M. MenchónJosé M. MenchónGemma Mestre-bachGemma Mestre-bach

subject

050103 clinical psychologymedicine.medical_specialtybusiness.industry05 social sciencesNeuropsychologyCognitionmedicine.diseaseResponse to treatmentIowa gambling task030227 psychiatry03 medical and health sciencesPsychiatry and Mental healthClinical PsychologyEating disorders0302 clinical medicineAnorexia nervosa (differential diagnoses)Internal medicinemedicineFull remission0501 psychology and cognitive sciencesIn patientbusinessClinical psychology

description

Background: Deficits in neuropsychological functioning have consistently been identified in patients with anorexia nervosa (AN). However, little is known on how decision making in AN patients evolves in response to treatment or whether impairments are reversible. Method: AN patients (n = 42) completed the Iowa Gambling Task (IGT) upon admission to a 3-month day-hospital treatment programme and at a 1-year follow-up. Patient IGT performance was compared to age-matched controls (n = 46). Results: AN patients displayed poorer performance on the IGT at admission compared to controls (p <.001). Patients with full remission (n = 31; 73.9%) at the 1-year follow-up improved IGT performance (p = 0.007), and scores were similar compared to controls (p = 0.557). AN patients with partial/no remission at follow-up (n = 11; 26.1%) did not improve IGT scores (p = 0.867). Conclusions: These findings uphold that enduring remission from AN can reverse decision-making impairments, and they might be most likely explained by clinical state rather than a trait vulnerability. Copyright © 2016 John Wiley & Sons, Ltd and Eating Disorders Association.

https://doi.org/10.1002/erv.2472