6533b861fe1ef96bd12c4261

RESEARCH PRODUCT

Cellular Acetylcholine Receptor Expression in the Brain of Patients with Alzheimer’s and Parkinson’s Dementia

Alfred MaelickeHannsjörg SchröderChristina LobronAndrea WeversEzio Giacobini

subject

business.industrymedicine.diseasePhenotypemedicine.anatomical_structureNeurochemicalCerebral cortexMuscarinic acetylcholine receptorMedicineDementiasense organsbusinessReceptorNeuroscienceAcetylcholine receptor

description

Binding studies and receptor autoradiography reveal the overall changes of acetylcholine receptors (AChR) in Alzheimer’s and Parkinson’s dementia cortices.2,5 A detailed account of these changes requires a study of neurochemical phenotype of individual neurons as basic elements of networks constituting the substrate of cortical functions.4 Examples will be given for cell-type specific AChR localization in normal and diseased human cerebral cortex.

yearjournalcountryeditionlanguage
1995-01-01
https://doi.org/10.1007/978-1-4757-9145-7_11