6533b861fe1ef96bd12c456b
RESEARCH PRODUCT
The case for simplifying and using absolute targets for viral hepatitis elimination goals
Tsendsuren S. OyunsurenChari CohenWaseem HamoudiYao‐chun HsuHarry L.a. JanssenHisham El KhayatManal H El-sayedWan-long ChuangYoung-suk LimMohamed HassanyFernando Passos Cupertino De BarrosFaisal AbaalkhailStefan ZeuzemSamual S LeeMiriam T. LevyImam WakedVassiliki PapaevangelouJames FungErika Castro BatänjerKathryn Razavi-shearerBoatemaa Ntiri‐ ReidRosmawati MohamedPagbajabyn NymadawaRobert FlisiakAlnoor RamjiCarole Seguin-devauxSherif MogawerBéla HunyadyHuma QureshiMojca MatičičMartin LaggingMark W. SonderupXiaoguang DouAnne OevrehusWilliam SievertEzequiel RidruejoAnn-sofi DubergAhad EshraghianR. P. ShanmugamArif NawazQing XieRick DunnSayed HimattDaniel ShouvalMendez Sanchez NahumSabahattin KaymakogluVincent Wai-sun WongSoek-siam TanWillis MaddreyPapu PrasadAmjad SalamatStephanie PoppingAlice LeeMaurizia Rossana BrunettoKhalid AlswatPeyton ThompsonDong Joon KimHenry ChangAmir Ali SohrabpourEllen DuganPeer Brehm ChristensenDavid A. M. C. Van De VijverJoaquín CabezasSu WangAla I. ShararaPeter JarcuskaKarine LacombeDanjuma AddaSammy SaabChien-jen ChenHwai I. YangSanaa SaidRaymond F. SchinaziShyamasundaran KottililGraham R. FosterQing NingMehlika ToyIra M. JacobsonAyat R. AbdallahLaura CisnerosDhondup TashiNaveed Z. JanjuaMoutaz DerbalaMarcelo KugelmasSteven L. FlammAngelos HatzakisYusuf YilmazMark S. SulkowskiEugene R. SchiffKakharman YesmembetovJohn F. DillonRittoo PrithiviputhCarlos Eduardo Brandão-melloRajender ReddyFrançoise Roudot-thoravalLewis R. RobertsJavier CrespoMassimo ColomboNancy SteinfurthI. M. HoepelmanKosh AgarwalFaisal M. SanaiWaleed Al-hamoudiShuang LiuBeat MuellhauptSonjelle ShiltonCurtis CooperCalvin Q. PanAijaz AhmedWai-cheung C LaoAlejandro SozaPatricia Vélez‐möllerIbrahim AltraifTarik AsselahJunko TanakaBadr AljarallahAdriana VinceFaryal KhamisJuan Francisco Sánchez-ávilaRafael Esteban MurKimberly A. BrownSaad Al-kaabiMing-lung YuJonas ValantinasMarieta SimonovaJavier García-samaniegoDo Young KimIeva TolmaneValentina LiakinaAntonio CraxìDevin Razavi-shearerWaldemar HalotaStuart K. RobertsDonna CryerKenneth KabagambeWilliam RemakJeffrey V. LazarusBrian ConwaySameera EzzatC Wendy SpearmanKarolin FalconerMaria C Mendes CorreaPoonam MathurFerruccio BoninoJose Luis CallejaSaid A. Al-busafiE. A. CroesTim BlockShahin MeratFrancesco NegroReza MalekzadehFernando L. GonçalesAmany ZekryWahid DossMichael NinburgPhilip BruggmannMan-fung YuenGeorge V. PapatheodoridisAasim YusufDavid KershenobichBruce R. BaconAbdul Rahman BizriGamal EsmatSarah BlachHamad Al-romaihiTatsuya KantoIbrahim MostafaHomie RazaviAlessio AghemoMauricio OrregoJia-horng KaoDaniel LavanchyZobair M. YounossiHenry Lik-yuen ChanAnna KramvisDavid H. MuljonoClemens RichterHla-hla TheinFernando BessonePaulo Roberto Abrão FerreiraGeoffrey DusheikoSusan HayGeert RobaeysEduardo FassioLoreta A. KondiliJorge MeraKhalid Al-naamaniAlaa OsmanSaleh A. AlqahtaniJoseph DoyleNecati ÖRmeciYee Tak HuiHeiner WedemeyerLaith Jamal Abu RaddadMasayuki KurosakiRui Tato MarinhoRobert G. GishZaigham AbbasSeiji YamadaGiada SebastianiCihan YurdaydinMaria ButiPaulo Ferrinhosubject
ddc:616Carcinoma HepatocellularHepatologyHepatitis Viral Humanbusiness.industryLiver Neoplasmsddc:616.07medicine.diseaseWorld Health OrganizationVirologydigestive system diseasesGoalInfectious DiseasesAbsolute (philosophy)SDG 3 - Good Health and Well-beingVirologymedicineHumansViral hepatitisbusinessGoalsHumandescription
The 69th World Health Assembly endorsed the Global Health Sector Strategy for Viral Hepatitis, embracing a goal to eliminate hepatitis infection as a public health threat by 2030. This was followed by the World Health Organization's (WHO) global targets for the care and management of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. These announcements and targets were important in raising awareness and calling for action; however, tracking countries’ progress towards these elimination goals has provided insights to the limitations of these targets. The existing targets compare a country's progress relative to its 2015 values, penalizing countries who started their programmes prior to 2015, countries with a young population, or countries with a low prevalence. We recommend that (1) WHO simplify the hepatitis elimination targets, (2) change to absolute targets and (3) allow countries to achieve these disease targets with their own service coverage initiatives that will have the maximum impact. The recommended targets are as follows: reduce HCV new chronic cases to ≤5 per 100 000, reduce HBV prevalence among 1-year-olds to ≤0.1%, reduce HBV and HCV mortality to ≤5 per 100 000, and demonstrate HBV and HCV year-to-year decrease in new HCV- and HBV-related HCC cases. The objective of our recommendations is not to lower expectations or diminish the hepatitis elimination standards, but to provide clearer targets that recognize the past and current elimination efforts by countries, help measure progress towards true elimination, and motivate other countries to follow suit.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2021-01-01 |