6533b861fe1ef96bd12c457c
RESEARCH PRODUCT
Nucleophilic additions of sodium alkoxides to 4,4-dichloro-1,1-diphenyl- 2-azabuta-1,3-diene
Sandrine JacquotMarek M. KubickiGérard SchmittBernard LaudeOlivier Blacquesubject
10120 Department of ChemistryDieneSodiumOrganic Chemistrychemistry.chemical_elementMedicinal chemistrySodium methoxideSodium saltchemistry.chemical_compoundchemistryNucleophile540 ChemistryAlkoxy groupOrganic chemistryPhysical and Theoretical Chemistry1606 Physical and Theoretical Chemistry1605 Organic Chemistrydescription
The reaction of some sodium alkoxides with 4,4-dichloro-1,1-diphenyl-2-azabuta-1,3-diene is described. Whereas sodium methoxide, ethoxide or isopropoxide leads to 1,3-bis(alkoxy)- and/or 1,3,4-tris(alkoxy)-2-azabut-2-enes, the sodium salt of ethyl glycolate gives a Δ2-oxazoline. Mechanisms for the formation of these products are proposed.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2000-04-01 |