6533b861fe1ef96bd12c4c3c
RESEARCH PRODUCT
The Chemokine Networks in Sponges: Potential Roles in Morphogenesis, Immunity and Stem Cell Formation
Heinz-christoph SchröderIsabel M. MüllerMatthias WiensW. E. G. Müllersubject
ChemokineImmune systembiologyPhylumImmunityPhylogeneticsCell adhesion moleculebiology.proteinMorphogenesisStem cellCell biologydescription
Porifera (sponges) are now well accepted as the phylum which branched off first from the common ancestor of all metazoans, the Urmetazoa. The transition to the Metazoa became possible because during this phase, cell-cell as well as cell-matrix adhesion molecules evolved which allowed the formation of a colonial stage of animals. The next prerequisite for the evolution to the Urmetazoa was the establishment of an effective immune system which, flanked by apoptosis, allowed the formation of a first level of individuation.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2003-01-01 |