6533b861fe1ef96bd12c4e8b

RESEARCH PRODUCT

CRT-605 Multimodality Imaging Demonstrating Liposomes Preferentially Home to Regions of Myocardial Injury

María Teresa AlbeldaDavid HellingaDror LugerAndrew E. AraiRon WaksmanJuan C. FriasWei SunStephen E. EpsteinMichael J. LipinskiStasia A. Anderson

subject

LiposomePathologymedicine.medical_specialtybusiness.industrycardiovascular systemmedicineMale micecardiovascular diseasesMyocardial infarctionmedicine.diseaseLigationbusinessCardiology and Cardiovascular Medicine

description

Nanoparticles may serve as a promising means to deliver novel therapeutics to the myocardium following myocardial infarction. We assessed whether lipid-based liposomal nanoparticles specifically target injured myocardium following intravenous injection. CD1 male mice that underwent LAD ligation

https://doi.org/10.1016/j.jcin.2014.12.164