6533b861fe1ef96bd12c4f93

RESEARCH PRODUCT

Omega-3 polyunsaturated fatty acids: Benefits and endpoints in sport

Maria Alessandra GammoneGaspare ParrinelloGraziano RiccioniNicolantonio D'orazio

subject

0301 basic medicineAntioxidantSettore MED/09 - Medicina InternaSports Nutritional Sciencesmedicine.medical_treatmentCellular functionslcsh:TX341-641InflammationReviewBioinformaticsOMEGA-3 POLYUNSATURATED FATTY ACIDS03 medical and health sciencesFatty Acids Omega-3medicineHumansExercisefunctional foodsNutritionSportchemistry.chemical_classificationInflammationOmega-3030109 nutrition & dieteticsNutrition and DieteticsHuman studiesbusiness.industrymarine bioactivesFunctional foodfood and beveragesSkeletal muscleMetabolismMarine bioactivemedicine.anatomical_structurechemistrySeafoodPUFAsmedicine.symptombusinesslcsh:Nutrition. Foods and food supplyPUFAFood SciencePolyunsaturated fatty acidHuman

description

The influence of nutrition has the potential to substantially affect physical function and body metabolism. Particular attention has been focused on omega-3 polyunsaturated fatty acids (n-3 PUFAs), which can be found both in terrestrial features and in the marine world. They are responsible for numerous cellular functions, such as signaling, cell membrane fluidity, and structural maintenance. They also regulate the nervous system, blood pressure, hematic clotting, glucose tolerance, and inflammatory processes, which may be useful in all inflammatory conditions. Animal models and cell-based models show that n-3 PUFAs can influence skeletal muscle metabolism. Furthermore, recent human studies demonstrate that they can influence not only the exercise and the metabolic response of skeletal muscle, but also the functional response for a period of exercise training. In addition, their potential anti-inflammatory and antioxidant activity may provide health benefits and performance improvement especially in those who practice physical activity, due to their increased reactive oxygen production. This review highlights the importance of n-3 PUFAs in our diet, which focuses on their potential healthy effects in sport.

10.3390/nu11010046http://hdl.handle.net/10447/414034