6533b861fe1ef96bd12c4fa1

RESEARCH PRODUCT

Candida glabrata meningitis and endocarditis: a late severe complication of candidemia

Claudia ImburgiaGiovanni M. GiammancoMarcello TrizzinoS. MadoniaClaudia ColombaLucia Siracusa

subject

Aortic valveMicrobiology (medical)AdultSettore MED/07 - Microbiologia E Microbiologia Clinicamedicine.medical_specialtySettore MED/17 - Malattie InfettiveIntrinsic resistanceCandida glabrataBiologylcsh:Infectious and parasitic diseasesAortic aneurysmCerebrospinal fluidmedicineEndocarditisHumanslcsh:RC109-216MeningitisSevere complicationCandida glabrataEndocarditisCandidemiaGeneral Medicinemedicine.diseasebiology.organism_classificationbacterial infections and mycosesSurgeryMeningitis Fungalmedicine.anatomical_structureInfectious Diseasescardiovascular systemFemaleCandida glabrata Candidemia Meningitis EndocarditisMeningitis

description

SummaryWe report an unusual case of Candida glabrata meningitis and endocarditis in a young Caucasian woman with a prosthetic aortic valve and suffering from a dissecting thoraco-abdominal aortic aneurysm. C. glabrata was isolated from culture of the cerebrospinal fluid. Candida infection of the central nervous system is an uncommon manifestation of disseminated infection due to Candida species. Our case report also highlights the intrinsic resistance of C. glabrata to azoles.

yearjournalcountryeditionlanguage
2014-12-01International Journal of Infectious Diseases
10.1016/j.ijid.2014.04.032http://dx.doi.org/10.1016/j.ijid.2014.04.032