6533b861fe1ef96bd12c5723

RESEARCH PRODUCT

Long-term outcome after drug-eluting stents implantation: Target lesion versus nontarget lesion repeated intervention

Stefano CasiniGiuseppe SinicropiTommaso GoriMassimo FineschiValerio ZacàCarlo Pierli

subject

Target lesionmedicine.medical_specialtybusiness.industrymedicine.medical_treatmentPercutaneous coronary interventionmedicine.diseaseSurgeryCoronary artery diseaseLesionAtherectomysurgical procedures operativeRestenosisDrug-eluting stentAngioplastymedicinecardiovascular diseasesRadiologymedicine.symptomCardiology and Cardiovascular Medicinebusinesstherapeutics

description

Abstract We sought to investigate the relative clinical significance of target and nontarget lesions repeated percutaneous coronary intervention (re-PCI) in patients implanted with drug-eluting stents (DES). Out of 2626 consecutive DES patients, we retrospectively selected 166 (6.3%; 123 males, aged 65±10years) who had a clinically-driven re-PCI over a mean follow-up of 15months. Seventy-five patients (45%) underwent the second procedure for disease progression in nontarget lesions (nontarget lesion re-PCI group) while 91 (55%) showed target lesion in-stent restenosis or thrombosis (target lesion re-PCI group), with no significant intergroup difference in the temporal trends of re-PCI. The prevalence of stable coronary artery disease and acute coronary syndromes (ACS) was 22% and 78% in the target lesion re-PCI vs. 81% and 19% in the nontarget lesion re-PCI group (overall p

yearjournalcountryeditionlanguage
2010-11-01International Journal of Cardiology
https://doi.org/10.1016/j.ijcard.2009.11.049