6533b861fe1ef96bd12c5795
RESEARCH PRODUCT
Effects of testosterone and β-glucan on immune functions in tench
Satu PaukkuJ. TaskinenJuhani PirhonenMarkus J. RantalaRaine KortetE. I. JokinenAnssi Vainikkasubject
chemistry.chemical_classificationmedicine.medical_specialtyHead KidneyPhagocytemedicine.drug_classSpleenTestosterone (patch)Aquatic ScienceBiologyAndrogenBasal (phylogenetics)Endocrinologymedicine.anatomical_structureImmune systemchemistryInternal medicinemedicineEcology Evolution Behavior and SystematicsGlucandescription
A hormone manipulation was performed to examine the effects of testosterone on basal and β-glucan-induced immune functions in wild-caught male and female tench Tinca tinca. Testosterone administration elevated testosterone concentration in plasma, but did not suppress lytic activity of plasma or the chemiluminescence response of blood or head kidney phagocytes in any of the three successive samples or in any of the treatment groups. Both testosterone and β-glucan administrations had a negative effect on the relative mass of the spleen, and testosterone-treated fish lost more mass than control fish. Males had a relatively larger spleen than females, but there were no gender differences in immune function. β-glucan-administration did not affect the plasma testosterone concentration.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2005-02-01 | Journal of Fish Biology |