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RESEARCH PRODUCT

Measurement of Human Tumor Blood Flow: A Positron Technique Using an Artifact of High Energy Radiation Therapy

Junhee LeePeter VaupelPaul Okunieff

subject

Human tumorArtifact (error)PhotonPositronMaterials scienceProtonbusiness.industryBlood flowIrradiationRadiationNuclear medicinebusiness

description

For at least three decades (1–6) there has been an interest in measuring tumor blood flow (TBF) and in the determination of its relation to the response of human tumors to radiation, drug therapies, and to the probability of development of distant metastases. The proton activation method which will be described below allows daily measurements of blood flow, in only 7 minutes, in patients being irradiated by photons of ≥20 MV, or by protons and other heavy particles.

https://doi.org/10.1007/978-1-4615-3428-0_17