6533b862fe1ef96bd12c6403

RESEARCH PRODUCT

Near fatal percutaneous paraquat poisoning

R. WronskiM. OkonekS. OkonekW. NiedermayerA. Lamer

subject

MaleParaquatinorganic chemicalsTime FactorsPercutaneousAccident preventionSkin AbsorptionPoison controlAbsorption (skin)LesionNecrosischemistry.chemical_compoundParaquatDrug DiscoveryAnimalsHumansMedicineheterocyclic compoundsGenetics (clinical)Skinintegumentary systembusiness.industryRats Inbred StrainsGeneral MedicinePARAQUAT POISONINGRatschemistryAccidents HomeChild PreschoolAnesthesiaMolecular MedicineDermal toxicityFemalemedicine.symptombusiness

description

A fatal paraquat poisoning can occur when relatively large areas of skin are contaminated with a concentrated solution of paraquat (Gramoxone). A paraquat absorption takes place of the same magnitude as that with an equal dose per os. In the presence of mechanical or chemical lesion of the skin the percutaneous paraquat absorption is distinctly enhanced.

https://doi.org/10.1007/bf01487582