6533b862fe1ef96bd12c647f
RESEARCH PRODUCT
The reaction of aromatic α,β-unsaturated ketones with 4,5-diamino-1,6- dihydropyrimidin-6-ones
A. SanchezNorbert HanoldJairo QuirogaMonica RamosBraulio InsuastyHerbert MeierManuel Noguerassubject
Chalconechemistry.chemical_compoundchemistryBicyclic moleculeDiamineOrganic ChemistryLactamOrganic chemistryEnoneDecoupling (electronics)description
The reaction of 4,5-diamino-1,6-dihydropyrimidin-6-ones 1 with one equivalent of the chalcones 2 leads in an acidic medium to the formation of the 2,4-diaryl-2,3,6,7-tetrahydro-1H-pyrimido[4,5-b][1,4]diazepin-6-ones 3a-m. The structure elucidation of the products is based on detailed nmr investigations including selective 13C[1H] decoupling experiments.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1994-01-01 |