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RESEARCH PRODUCT
Relationship between device acceptance and patient-reported outcomes in Left Ventricular Assist Device (LVAD) recipients
Gregory A. EwaldCrispino TostoHeidi CraddockMaria Di BlasiLuigi AdamoRosario GirgentiFrancesco ClemenzaRobert M. Carneysubject
AdultMaleQuality of life0301 basic medicinemedicine.medical_specialtyGeneralized anxiety disorderdevice acceptance.body imagemedicine.medical_treatmentPsychological interventionlcsh:MedicineHeart failureArticle03 medical and health sciences0302 clinical medicineQuality of lifemedicineHumansPatient Reported Outcome Measureslcsh:ScienceDepression (differential diagnoses)AgedCardiac device therapyAged 80 and overMultidisciplinarybusiness.industrylcsh:RMiddle Agedmedicine.diseaseLeft Ventricular Assist Deviceanxiety3. Good healthPatient Health QuestionnaireDistress030104 developmental biologyOutcomes researchVentricular assist devicedepressionPhysical therapyAnxietyFemalelcsh:QHeart-Assist Devicesmedicine.symptombusiness030217 neurology & neurosurgerydescription
AbstractThe number of Left Ventricular Assist Devices (LVADs) implanted each year is rising. Nevertheless, there are minimal data on device acceptance after LVAD implant, and on its relationship with patient-reported outcomes. We designed a cross-sectional study to address this knowledge gap and test the hypothesis that low device acceptance is associated with poorer quality of life, depression and anxiety. Self-report questionnaires were administered to assess quality of life (12-item Kansas City Cardiomyopathy Questionnaire quality of life subscale), level of anxiety (7-item Generalized Anxiety Disorder; GAD-7), level of depression (9-item Patient Health Questionnaire; PHQ-9) and device acceptance (Florida Patient Acceptance Survey; FPAS) to 101 consecutive patients presenting to LVAD clinic. Regression analysis showed a strong correlation between device acceptance and both psychological distress (p < 0.001) and quality of life (p < 0.001). Analysis of the sub-scales of the FPAS showed that patients had significant body image concerns, but return to function and device-related distress were the main drivers of the observed correlation between device acceptance and patient well-being. Younger age was associated with lower device acceptance (r = 0.36, p < 0.001) and lower quality of life (r = 0.54, p < 0.001). These findings suggest that interventions targeting device acceptance should be explored to improve outcomes in LVAD recipients.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2019-07-01 | Scientific Reports |