6533b862fe1ef96bd12c6db5
RESEARCH PRODUCT
Endothelial Wnt/β-catenin signaling inhibits glioma angiogenesis and normalizes tumor blood vessels by inducing PDGF-B expression
Marco ReisSascha SeidelMakoto Mark TaketoCathrin J. CzupallaErnesto BockampJadranka MacasStefan LiebnerSonja ThomJenny ZinkeKarl H. PlateKavi DevrajStefanie DimmelerRosario HeckNicole ZieglerMarcus Fruttigersubject
PathologyAngiogenesisCentral Nervous System NeoplasmsMice0302 clinical medicineImmunology and AllergyWnt Signaling Pathwaybeta Catenin0303 health sciencesbiologyNeovascularization PathologicBrain NeoplasmsWnt signaling pathwayIntracellular Signaling Peptides and ProteinsForkhead Transcription FactorsGliomaProto-Oncogene Proteins c-sis3. Good healthmedicine.anatomical_structureBlood-Brain Barrier030220 oncology & carcinogenesiscardiovascular systemIntercellular Signaling Peptides and ProteinsFemalemedicine.medical_specialtyBeta-cateninEndotheliumImmunologyNotch signaling pathwayMice NudeWnt1 ProteinMural cellArticle03 medical and health sciencesGliomamedicineAnimalsHumansddc:610neoplasms030304 developmental biologyAdaptor Proteins Signal TransducingCalcium-Binding ProteinsMembrane Proteinsmedicine.diseaseXenograft Model Antitumor Assaysnervous system diseasesDKK1Cancer researchbiology.proteinEndothelium VascularNeoplasm Gradingdescription
Wnt modulates glioma vascularization by regulating PDGF-B expression.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2012-08-20 |