6533b862fe1ef96bd12c6eb2
RESEARCH PRODUCT
Oral Propranolol for Circumscribed Choroidal Hemangioma
Manuel Díaz-llopisRoberto GallegoEmpar Sanz-marcosubject
medicine.medical_specialtyVisual acuityEndotheliumCircumscribed choroidal hemangiomaPropranololβ-Blockerlcsh:OphthalmologyOphthalmologymedicineCircumscribed choroidal hemangiomaAdverse effectRetinaEndothelial proliferationbusiness.industryβ-Blockereye diseasesSurgeryOphthalmologyPublished: February 2011medicine.anatomical_structurelcsh:RE1-994sense organsmedicine.symptombusinessVasoconstrictionmedicine.drugPropanololdescription
Introduction: Several therapeutic approaches have been developed to treat choroidal hemangioma. However, all these therapies are associated with a potential risk of damaging the overlying retina. Case Report: We report a case of circumscribed choroidal hemangioma (CCH) in a 59-year-old man refractory to laser treatment. Visual acuity was 20/200 and a serous macular detachment was present. The CCH was treated with oral propanolol, whereupon visual acuity improved to 20/20 and the macular detachment resolved without systemic or local adverse effects. Discussion: Propanolol is a β-blocker commonly used in cardiology that may induce endothelium vasoconstriction and inhibit endothelial proliferation. It has been shown to be effective in infantile facial hemangiomas, and proved safe and effective for the CCH in our patient. Further studies are needed to confirm our observation.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2011-02-01 | Case Reports in Ophthalmology |