Induction of apoptosis in human osteosarcoma Saos-2 cells by the proteasome inhibitor MG132 and the protective effect of pRb

6533b862fe1ef96bd12c7737

RESEARCH PRODUCT

Induction of apoptosis in human osteosarcoma Saos-2 cells by the proteasome inhibitor MG132 and the protective effect of pRb

Giovanni Tesoriere Michela Giuliano Renza Vento Antonella D'anneo Giuseppe Calvaruso Sonia Emanuele Marianna Lauricella

subject

Time Factors Leupeptins Apoptosis Retinoblastoma Protein Antioxidants Amino Acid Chloromethyl Ketones Membrane Potentials chemistry.chemical_compound Settore BIO/10 - Biochimica MG132 Caspase 8 Osteosarcoma Chemistry Caspase 3 Cytochromes c Flow Cytometry Mitochondria Cysteine Endopeptidases Proto-Oncogene Proteins c-bcl-2 Caspases Osteosarcoma medicine.drug musculoskeletal diseases Proteasome Endopeptidase Complex Cell Survival Blotting Western bcl-X Protein macromolecular substances Transfection Multienzyme Complexes Cell Line Tumor parasitic diseases medicine Humans Protease Inhibitors neoplasms Molecular Biology Saos-2 cells Dose-Response Relationship Drug Cell Biology medicine.disease Acetylcysteine Apoptosis osteosarcoma proteasome inhibitors Microscopy Fluorescence Apoptosis Cancer research Proteasome inhibitor Tumor Suppressor Protein p53 Reactive Oxygen Species human activities

description

Induction of apoptosis in human osteosarcoma Saos-2 cells by the proteasome inhibitor MG132 and the protective effect of pRb

year	journal	country	edition	language
2003-07-18

10.1038/sj.cdd.4401251 http://hdl.handle.net/10447/65762

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