Bidentatoside I, a New Triterpene Saponin from Achyranthes bidentata

6533b86cfe1ef96bd12c814b

RESEARCH PRODUCT

Bidentatoside I, a New Triterpene Saponin from Achyranthes bidentata

Anne Claire Mitaine-offer Cosimo Pizza Bruno Chauffert Tran Cong Khanh Abderrazak Marouf Marie Aleth Lacaille-dubois

subject

Magnetic Resonance Spectroscopy Stereochemistry Saponin Pharmaceutical Science Antineoplastic Agents Uronic acid Pharmacognosy Analytical Chemistry Magnoliopsida chemistry.chemical_compound Triterpene Drug Discovery Tumor Cells Cultured Humans Achyranthes bidentata Pharmacology chemistry.chemical_classification biology Organic Chemistry Glycoside Saponins biology.organism_classification Triterpenes Terpenoid Models Chemical Complementary and alternative medicine chemistry Biochemistry Heteronuclear molecule Colonic Neoplasms Molecular Medicine Drug Screening Assays Antitumor

description

Bidentatoside I (1) is a new triterpene saponin bearing an unusual dioxopropionic acid unit, isolated from the roots of Achyranthes bidentata. Structural elucidation was performed mainly by chemical and homo- and heteronuclear 2D NMR techniques. This compound did not show any potentiation of the in vitro cytotoxicity of cisplatin in the HT 29 human colon cancer cell line.

year	journal	country	edition	language
2001-01-20	Journal of Natural Products

https://doi.org/10.1021/np000464a

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