6533b86cfe1ef96bd12c835a
RESEARCH PRODUCT
Data comparison between pharmacological induction of labour and spontaneous delivery. A single centre experience.
Angela SiciliaRoberta GrassoOnofrio TrioloGaspare CucinellaAlessandro SollanoGloria CalagnaStefania MondelloRoberta Granesesubject
Adultmedicine.medical_specialtyTime FactorsProstaglandin E2Cohort Studies03 medical and health sciences0302 clinical medicineObstetrics and gynaecologyPregnancy030225 pediatricsSpontaneous labourOxytocicsInduction of labourMedicineInduction of labour Neonatal outcome Prostaglandin E2 Spontaneous labour Medicine (all) Obstetrics and GynecologyHumans030212 general & internal medicineLabor InducedProstaglandin E2reproductive and urinary physiologyGynecologyFetusbusiness.industryObstetricsInfant NewbornPregnancy OutcomeObstetrics and GynecologyGestational ageSpontaneous labourFetal PresentationNeonatal outcomeDelivery ObstetricSingle centreProstaglandinsFemalebusinessCohort studymedicine.drugdescription
Objectives: To assess the differences in the maternal and fetal outcomes between pharmacological induced and spontaneous labour in nulliparous women. Material and methods: Observational cohort study carried out over a period of 2 years. Inclusion criteria: nulliparous singleton pregnancies, with cephalic fetal presentation, elective labour induction with intra-vaginal prostaglandin E2 (PGE2) gel (Prepidil® 2 mg) at a gestational age of 41 weeks. Control group: patients who entered labour spontaneously at a gestational age of ≥ 40 weeks. The main demographic maternal characteristics and intra- and postpartum data were extracted from computer records and obstetrics diaries and were used for the analysis. Results: One hundred and three patients with induction of labour and 97 with spontaneous labour were enrolled. Cesarean delivery was performed in 18 cases (17.5%), all in the induction group. There were no differences in newborn weights between the 2 groups while both the 1-minute and 5-minute Apgar scores were significantly higher in the spontaneous group (p = 0.014 and p = 0.0003, respectively). Women in the induction group had a significantly longer duration of I stage labour in comparison with spontaneous group (p < 0.0001). Conclusions: Primiparous women whose labour was induced spent a longer time in labour than women who presented in spontaneous labour. Clinicians should keep in mind that a slow rate of dilation in a woman being induced may be normal. For this reason, an arrest diagnosis needs to be carefully considered.
year | journal | country | edition | language |
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2016-01-01 | Ginekologia polska |