6533b86cfe1ef96bd12c8396

RESEARCH PRODUCT

Column-switching techniques for high-performance liquid chromatography of drugs in biological samples.

Rosa Herráez-hernándezAdela Sevillano-cabezaPilar Campí Ns-falcó

subject

AnalyteChromatographyChemistryGeneral ChemistryHigh-performance liquid chromatographyBiological materialsChromatographic separationColumn chromatographyPharmaceutical PreparationsAnimalsHumansColumn switchingDrug analysisQuantitative analysis (chemistry)Chromatography High Pressure Liquid

description

In recent years, an increasing number of publications have demonstrated the potential of column-switching techniques for the chromatographic separation, determination and preparative isolation of analytes from biological matrices. Column-switching systems greatly facilitate drug analysis, by on-line sample clean-up and trace enrichment, or by improving the analytical separative process. In this paper, the main applications of column-switching techniques to drug analysis in biological samples, are reviewed.

yearjournalcountryeditionlanguage
1993-09-22Journal of chromatography
10.1016/0378-4347(93)80107-fhttps://pubmed.ncbi.nlm.nih.gov/8263090