6533b86cfe1ef96bd12c85f3
RESEARCH PRODUCT
Documento di consenso intersocietario ANMCO/ISS/AMD/ANCE/ARCA/FADOI/ GICR-IACPR/SICI-GISE/SIBioC/SIC/SICOA/ SID/SIF/SIMEU/SIMG/SIMI/SISA Colesterolo e rischio cardiovascolare: percorso diagnostico-terapeutico in Italia
Michele Massimo GuliziaFurio ColivicchiGualtiero RicciardiSimona GiampaoliAldo Pietro MaggioniMaurizio AvernaMaria Stella GrazianiFerruccio CeriottiAlessandro MugelliFrancesco RossiGerardo MedeaDamiano ParrettiMaurizio Giuseppe AbrignaniMarcello ArcaPasquale Perrone FilardiFrancesco PerticoneAlberico CatapanoRaffaele GriffoFederico NardiCarmine RiccioAndrea Di LenardaMarino ScherilloNicoletta MusacchioAntonio Vittorio PannoGiovanni Battista ZitoMauro CampaniniLeonardo BolognesePompilio Massimo FaggianoGiuseppe MusumeciEnrico PusineriMarcello CiaccioEnzo BonoraGiorgio Cantelli FortiMaria Pia RuggieriClaudio CricelliFrancesco RomeoRoberto FerrariAttilio Maserisubject
Settore BIO/12 - Biochimica Clinica E Biologia Molecolare ClinicaSettore MED/09 - Medicina InternaItalyCardiovascular DiseaseRisk FactorAnticholesteremic AgentHypercholesterolemiaSettore BIO/14 - FarmacologiaConsensuCardiology and Cardiovascular MedicineSettore MED/11 - Malattie Dell'Apparato CardiovascolareHumandescription
Atherosclerotic cardiovascular disease still represents the leading cause of death in western countries. A wealth of scientific evidence demonstrates that increased blood cholesterol levels have a major impact on the outbreak and progression of atherosclerotic plaques. Moreover, several cholesterol-lowering pharmacological agents, including statins and ezetimibe, have proven effective in improving clinical outcomes. This document is focused on the clinical management of hypercholesterolemia and has been conceived by 16 Italian medical associations with the support of the Italian National Institute of Health. The authors have considered with particular attention the role of hypercholesterolemia in the genesis of atherosclerotic cardiovascular disease. Besides, the implications of high cholesterol levels in the definition of the individual cardiovascular risk profile have been carefully analyzed, while all available therapeutic options for blood cholesterol reduction and cardiovascular risk mitigation have been considered. Finally, this document outlines the diagnostic and therapeutic pathways for the clinical management of patients with hypercholesterolemia.
year | journal | country | edition | language |
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2016-01-01 |