6533b86cfe1ef96bd12c8932
RESEARCH PRODUCT
Orientation, recognition, and photoreaction of nucleolipids in model membranes
Helmut RosemeyerMichael AhlersHelmut RingsdorfFrank Seelasubject
Polymers and PlasticsStereochemistrytechnology industry and agricultureSynthetic membraneNucleobaseDouble chainCrystallographychemistry.chemical_compoundColloid and Surface ChemistryMonomerMembranechemistrySolubilizationMonolayerAmphiphileMaterials ChemistryPhysical and Theoretical Chemistrydescription
Amphiphiles with nucleobases and nucleosides as headgroups have been synthesized. Their surface behavior was investigated in monolayers at the air/water interface. The double chain nucleolipids form stable monolayers with nearly identical surface pressure-area diagrams, whereas the spreading behavior of the mono chain amphiphiles is dominated by the various nucleobase-headgroups. When measuring the interactions between nucleolipid monolayers and nucleobases (monomeric and polymeric ones), specific base-base effects could be observed: the complementary nucleobases solubilized in the subphase expand the monolayer more than the non-complementary ones. Photodimerization reactions of thymine-amphiphiles were investigated in mono- and multilayers as well as in spin-coated films.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1990-02-01 | Colloid & Polymer Science |