6533b86cfe1ef96bd12c8945
RESEARCH PRODUCT
Chemically induced chromosome damage in early-developing embryos ofAnilocra physodes L. (Crustacea, Isopoda) following exposure to bis[Dimethyltin(IV)Chloro]protoporphyrin IX
E. CatalanoRoberto VitturiM. R. Lo ConteLorenzo Pelleritosubject
Protoporphyrin IXChemistryStereochemistryChromosomeEmbryoGeneral ChemistryMolecular biologyInorganic Chemistrychemistry.chemical_compoundChromosome regionsProtoporphyrinMetaphaseDNAAnaphasedescription
In order to obtain chromosome preparations from early-developing embryos of Anilocra physodes, a squash technique has been successfully employed. Results gathered after exposure of this material to bis[dimethyltin(IV)chloro]protoporphyrin IX {[(CH3)2SnCl]2 - Protoporphyrin IX} solutions at different exposure times suggest that this chemical complex is capable of producing abnormal metaphase and anaphase figures in proportion to its concentration and not to exposure length. Essentially, all of the chromosome abnormalities are classifiable as chromosome fragments mainly observed at the metaphase stage; chromosome bridges; and large decondensed chromosome regions.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1993-09-01 | Applied Organometallic Chemistry |