6533b86cfe1ef96bd12c89c6

RESEARCH PRODUCT

Asymmetric and Symmetric Dicopper(II) Paddle-Wheel Units with Modified Nucleobases

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description

New copper(II) paddle-wheel complexes with different modified nucleobases and simple molecules in the axial positions have been prepared by direct reactions between copper(II) salts and the corresponding uracil- or thymine-1-acetic acids under inert atmosphere to produce the two homoleptic complexes, [Cu2(μ-OOCCH2-T)4(G)2] and [Cu2(μ-OOCCH2-U)4(G)2], and the heteroleptic one [Cu2(μ-OOCCH2-T)2(μ-OOCCH2-U)2(G)2] (where OOCCH2-T = thymine-1-acetate, OOCCH2-U = uracil-1-acetate, and G = dimethylformamide, water, dimethylacetamide, or dimethyl sulfoxide). Interestingly, the crystal structures of this family of closely related molecules present significant differences in their supramolecular arrangements affecting the crystal networks mainly due to the interactions defined between the different apical ligands and the coordinated modified nucleobases. Thus, depending upon the dimetallic complex several H-bonding interactions have been found in these series: (i) base pairing through Watson–Crick faces of adjacent...