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RESEARCH PRODUCT

La resonancia magnética y el índice MaRIA en la valoración preoperatoria de la enfermedad de Crohn ileal

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Abstract Introduction Accurate quantification of the inflammatory activity in Crohn’s Disease is essential to decide the adequate treatment for each patient. The aim of the present study is to assess the correlation between the pre-operative Magnetic Resonance Index of Activity (MaRIA) and the histologic degree of inflammation from surgically resected intestinal Crohn’s Disease lesions. Methods This is a prospective study including a consecutive case series of patients with small bowel Crohn’s Disease, who underwent surgical resection. A Magnetic Resonance Enterography was performed during the three months prior to surgery, applying a pre-established protocol. Relative contrast enhancements, wall thickness, presence of edema or ulcerations were the parameters used to calculate the MaRIA Index. All patients underwent surgery and every specimen was analysed. The modified Chiorean classification was applied for the histological analysis and an ordinal regression analysis was used in order to correlate MaRIA and the grade of inflammation for each lesion. Results 59 lesions from 35 different patients were analysed. The degree of inflammation of the lesions was statistically correlated to the MaRIA values (P = .002). The MaRIA index was significantly different (P  Conclusion MaRIA is a reliable tool to distinguish inflammatory from fibrotic lesions; therefore, it could be considered crucial to determine the most appropriate Crohn’s Disease treatment for each patient.