Short and Efficient Chemoenzymatic Synthesis of Goniothalamin.

6533b86dfe1ef96bd12c9588

RESEARCH PRODUCT

Short and Efficient Chemoenzymatic Synthesis of Goniothalamin.

Renato Noto Michelangelo Gruttadauria Paolo Lo Meo

subject

Acrylate Organic Chemistry Settore CHIM/06 - Chimica Organica General Medicine Metathesis Biochemistry Kinetic resolution goniothalamin chemistry.chemical_compound chemistry Drug Discovery lipase Organic chemistry delta-lactone

description

A high-yielding three-step synthesis of goniothalamin involving an enzymatic kinetic resolution in the presence of vinyl acrylate followed by ring-closing metathesis is discussed.

year	journal	country	edition	language
2004-03-30	ChemInform

https://doi.org/10.1002/chin.200413203

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