Search results for "Acrylate"

showing 10 items of 554 documents

Reactivity of [1,2,3]Triazolo[1,5-a]pyridines as 1,3-dipoles

2016

Abstract We have studied the reactions between [1,2,3]Triazolo[1,5- a ]pyridines 1a,b,c and electron-deficient ethylenes in different conditions. Compounds 1a and 1b react with ethyl propiolate, and dimethyl acetylene dicarboxylate giving a new class of biaryl compounds pyridyl pyrazoles, and with ethyl acrylate giving pyridyl cyclopropanes. Compound 1c did not give any product in the studied conditions. A proposal of mechanism of these reactions is done in which the triazolopyridines act as 1,3-dipoles giving 1,3-dipolar cycloadditions.

010405 organic chemistryChemistryOrganic Chemistry010402 general chemistry01 natural sciencesBiochemistry0104 chemical sciencesEthyl propiolatechemistry.chemical_compoundAcetyleneDrug DiscoveryPolymer chemistryEthyl acrylateReactivity (chemistry)Tetrahedron
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How Many Phosphoric Acid Units Are Required to Ensure Uniform Occlusion of Sterically Stabilized Nanoparticles within Calcite?

2019

Polymerization-induced self-assembly (PISA) mediated by reversible addition-fragmentation chain transfer (RAFT) polymerization offers a platform technology for the efficient and versatile synthesis of well-defined sterically stabilized block copolymer nanoparticles. Herein we synthesize a series of such nanoparticles with tunable anionic charge density within the stabilizer chains, which are prepared via statistical copolymerization of anionic 2-(phosphonooxy)ethyl methacrylate (P) with non-ionic glycerol monomethacrylate (G). Systematic variation of the P/G molar ratio enables elucidation of the minimum number of phosphate groups per copolymer chain required to promote nanoparticle occlusi…

010405 organic chemistryNanoparticleChain transferGeneral ChemistryRaftGeneral Medicine010402 general chemistryMethacrylate01 natural sciencesCatalysis0104 chemical scienceschemistry.chemical_compoundchemistryPolymerizationChemical engineeringCopolymerReversible addition−fragmentation chain-transfer polymerizationPhosphoric acidAngewandte Chemie
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The effect of incorporating different concentrations of chlorhexidine digluconate on the degree of conversion of an experimental adhesive resin

2018

Background The aim of this study was to evaluate the effect of chlorhexidine digluconate incorporation on the degree of conversion of an experimental adhesive resin. Material and Methods The experimental resin was prepared from 70 wt% bisphenol A glycerolate dimethacrylate, 30 wt% hydroxyethyl methacrylate, silanized SiO2 nanofillers, 0.5% of camphorquinone and ethyl 4-dimethylaminebenzoate (binary photo-initiator system). Five chlorhexidine digluconate concentrations (0, 0.5, 1, 2 and 4 wt%) were then incorporated into the experimental resin. Thirty Potassium Bromide pellets were prepared then divided into six groups (n=5/group), repre¬senting the tested adhesive resins (Single Bond 2, 0, …

0301 basic medicineBisphenol AChemistryPotassium bromideResearchChlorhexidinePellets030206 dentistry(Hydroxyethyl)methacrylate:CIENCIAS MÉDICAS [UNESCO]Operative Dentistry and Endodontics03 medical and health scienceschemistry.chemical_compound030104 developmental biology0302 clinical medicinePolymerizationUNESCO::CIENCIAS MÉDICASmedicineAdhesiveFourier transform infrared spectroscopyGeneral DentistryNuclear chemistrymedicine.drug
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Antibacterial properties and reduction of MRSA biofilm with a dressing combining polyabsorbent fibres and a silver matrix

2016

Objective: This study was designed to evaluate the antibacterial activity of a wound dressing which combines polyacrylate fibres and a silver lipido-colloid matrix (UrgoClean Ag, silver polyabsorbent dressing), against biofilm of methicillin-resistant Staphylococcus aureus (MRSA). Method: Samples of silver polyabsorbent dressing and the neutral form of this dressing (UrgoClean) were applied to biofilms of MRSA formed on a collagen I-coated surface, cultured for 24 hours. Different exposure times were tested (1, 2, 4 and 7 days) without dressing change. The biofilm reduction was quantified by using culture methods and by confocal laser scanning microscopy experiments. Results: The applicatio…

0301 basic medicineColonizationNursing (miscellaneous)ResistanceMechanical effectMRSAmedicine.disease_causeDressing changeMatrix (chemical analysis)030207 dermatology & venereal diseases0302 clinical medicine[SDV.IDA]Life Sciences [q-bio]/Food engineeringContaining wound dressingseducation.field_of_studyBiofilm[ SDV.IDA ] Life Sciences [q-bio]/Food engineeringSilver CompoundsHydrogelsAnti-Bacterial AgentsStaphylococcus aureusSilver-containing wound dressingPseudomonas aeruginosaPolyacrylate fibresAntibacterial activityMethicillin-Resistant Staphylococcus aureus030106 microbiologyPopulationStaphylococcus-aureus biofilmBurnMicrobiology03 medical and health sciencesmedicineConfocal laser scanning microscopyHumansPseudomonas-aeruginosa biofilmeducationWound HealingBacteriaPseudomonas aeruginosabusiness.industryIn-vitro modelHuman keratinocytesBiofilmbiochemical phenomena metabolism and nutritionBandagesBiofilmsWound InfectionAntimicrobial efficacyFundamentals and skillsAntibacterial activitybusinessNuclear chemistry
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Effect of rinsing time and surface contamination on the bond strength of silorane-based and dimethacrylate-based composites to enamel

2018

Background The aim of this study was to assess whether saliva contamination and rinsing time for 15, 30, and 60 seconds, affects the shear bond strength of silorane and methacrylate-based composites to enamel. Material and Methods Two light cure resin, P60 (3M ESPE) and Filtek LS Silorane were tested. 120 sound premolars were randomly divided into four groups of 30 teeth based on composite type with or without saliva contamination after etching and rinsing. Each group was further divided into three subgroups according to their rinsing time. Then a cylinder of the composite was bonded to the enamel and Shear bond strength was assessed. To determine the failure mode, the bonded surfaces were …

0301 basic medicineMaterials scienceEnamel paintBond strengthResearchComposite number030206 dentistryContaminationMethacrylate:CIENCIAS MÉDICAS [UNESCO]Operative Dentistry and Endodontics03 medical and health sciences030104 developmental biology0302 clinical medicineLeast significant differencestomatognathic systemvisual_artUNESCO::CIENCIAS MÉDICASvisual_art.visual_art_mediumShear strengthAdhesiveComposite materialGeneral Dentistry
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Influence of Polyplex Formation on the Performance of Star-Shaped Polycationic Transfection Agents for Mammalian Cells

2016

Genetic modification (“transfection”) of mammalian cells using non-viral, synthetic agents such as polycations, is still a challenge. Polyplex formation between the DNA and the polycation is a decisive step in such experiments. Star-shaped polycations have been proposed as superior transfection agents, yet have never before been compared side-by-side, e.g., in view of structural effects. Herein four star-shaped polycationic structures, all based on (2-dimethylamino) ethyl methacrylate (DMAEMA) building blocks, were investigated for their potential to deliver DNA to adherent (CHO, L929, HEK-293) and non-adherent (Jurkat, primary human T lymphocytes) mammalian cells. The investigated vectors …

0301 basic medicinePDMAEMAPolymers and PlasticsBiocompatibilityStereochemistrynon-viralT lymphocytes02 engineering and technologyMethacrylateJurkat cellsMicelleArticlelcsh:QD241-44103 medical and health scienceschemistry.chemical_compoundlcsh:Organic chemistrymammalian cellsgene deliverychemistry.chemical_classificationGeneral ChemistryTransfectionPolymer021001 nanoscience & nanotechnologySilsesquioxane030104 developmental biologychemistrytransfectionBiophysics0210 nano-technologygene delivery; mammalian cells; non-viral; PDMAEMA; T lymphocytes; transfectionDNAPolymers
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Reactions of the hydrofluoroborate salts of open-chain analogues of Reissert compounds with some α,β-ethylenic esters

1999

The reaction of the hydrofluoroborate salt of an open-chain analogue of a Reissert compound with some α,β-ethylenic esters does not give a [4 + 2] cycloadduct, as previously described in the case of ethyl acrylate. The reaction starts with a 1,3-dipolar cycloaddition of a munchnone imine 5c, d. The [3 + 2] cycloadducts 13 evolve via a rearrangement–condensation sequence to give a substituted 2-pyridone derivative 18 or 19. The proposed mechanism has been verified by the isolation and structural X-ray analysis of some compounds of the reaction sequence.

10120 Department of Chemistrychemistry.chemical_classificationOrganic ChemistryImineSalt (chemistry)Azomethine ylideSequence (biology)Medicinal chemistryCycloadditionchemistry.chemical_compoundchemistry540 Chemistry13-Dipolar cycloadditionEthyl acrylatePhysical and Theoretical Chemistry1606 Physical and Theoretical ChemistryDerivative (chemistry)1605 Organic Chemistry
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Acid‐Cleavable Poly(ethylene glycol) Hydrogels Displaying Protein Release at pH 5

2020

Abstract PEG is the gold standard polymer for pharmaceutical applications, however it lacks degradability. Degradation under physiologically relevant pH as present in endolysosomes, cancerous and inflammatory tissues is crucial for many areas. The authors present anionic ring‐opening copolymerization of ethylene oxide with 3,4‐epoxy‐1‐butene (EPB) and subsequent modification to introduce acid‐degradable vinyl ether groups as well as methacrylate (MA) units, enabling radical cross‐linking. Copolymers with different molar ratios of EPB, molecular weights (M n) up to 10 000 g mol−1 and narrow dispersities (Đ<1.05) were prepared. Both the P(EG‐co‐isoEPB)MA copolymer and the hydrogels showed pH‐…

540 Chemistry and allied sciencesVinyl CompoundsBiocompatible MaterialsDegree of polymerization010402 general chemistry01 natural sciencesCatalysisPolyethylene GlycolsPolymerizationchemistry.chemical_compoundHydrolysisPolymer chemistryPEG ratioCopolymermedicinehydrogelsPolymer Technologieschemistry.chemical_classificationFull PaperEthylene oxide010405 organic chemistryHydrolysisOrganic ChemistryBiochemistry and Molecular BiologyProteinsprotein releaseHydrogelsGeneral ChemistryPolymerFull PapersHydrogen-Ion ConcentrationVinyl etherPolymerteknologiPEG0104 chemical sciencescopolymerizationchemistry540 Chemiedrug deliverySelf-healing hydrogelsMethacrylatesBiokemi och molekylärbiologimedicine.drugChemistry – A European Journal
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CCDC 1006013: Experimental Crystal Structure Determination

2018

Related Article: Valeria Corne, Ariel M. Sarotti, Carmen Ramirez de Arellano, Rolando A. Spanevello, Alejandra G. Suárez|2016|Beilstein J.Org.Chem.|12|1616|doi:10.3762/bjoc.12.158

9-((4-(trifluoromethyl)phenoxy)methyl)-522-dioxahexacyclo[7.6.6.136.028.01015.01621]docosa-101214161820-hexaen-7-yl acrylateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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Characterization of particle morphology of biochanin A molecularly imprinted polymers and their properties as a potential sorbent for solid-phase ext…

2014

Abstract Molecularly imprinted polymers (MIPs) with biochanin A as a template were obtained using a bulk polymerization with non-covalent imprinting approach. The polymers were prepared in acetonitrile as porogen, using ethylene glycol dimethacrylate (EDMA) as cross-linking agent. The synthesis, with an application of 1′,1′-azobis(cyclohexanecarbonitrile) (ACHN) as an initiator, has been performed thermally. During the synthesis process the effect of different functional monomers such as methacrylic acid (MAA), acrylamide (AA) and 4-vinylpyridine (4-VP) was investigated. The application of nitrogen sorption porosimetry, scanning electron microscopy (SEM), and Fourier transform infrared spec…

AcetonitrilesMaterials scienceNitrogenPolymersPyridinesEthylene glycol dimethacrylateBioengineeringPolymerizationBiochanin ABiomaterialschemistry.chemical_compoundSpectroscopy Fourier Transform Infraredsolid-phase extractionSolid phase extractionFourier transform infrared spectroscopyChromatography High Pressure Liquidchemistry.chemical_classificationphytoestrogensAcrylamideChromatographySolid Phase ExtractionMolecularly imprinted polymerPolymerGenisteinIsoflavonesCross-Linking ReagentschemistryMethacrylic acidMechanics of MaterialsadsorptionMicroscopy Electron ScanningMethacrylatesmolecular imprintingMolecular imprintingNuclear chemistryMaterials Science & Engineering C-Materials for Biological Applications
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