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RESEARCH PRODUCT
The Renal Dangers of an Increased Cardio-Ankle Vascular Index
Giuseppe MulèSantina CottoneMaria VadalàMaria Giovanna VarioNicola Sinatrasubject
medicine.medical_specialtyBlood PressurePulse Wave AnalysisKidneyRisk AssessmentVascular StiffnessRisk Factorsarterial stiffneInternal medicineInternal MedicinemedicineHumansAnkle Brachial IndexCardio-ankle vascular indexRenal Insufficiency ChronicKidneybusiness.industrycardio-ankle vascular indexPrognosismedicine.diseasemedicine.anatomical_structurePulsatile FlowHypertensionArterial stiffnessCardiologybusinesschronic kidney diseasedescription
Although a number of longitudinal investigations assessed the ability of aortic PWV to predict the development of kidney disfunction or progression of renal disease, little is known about the association of CAVI with the risk of renal function deterioration. In the current issue of the American Journal of Hypertension is published a paper of Itano S et al, that add a new piece of evidence in this scenario. The authors analyzed data from the national health check-up system in Japan, including 24.297 participants with normal baseline kidney function. They found that those with CAVI measurements ≥8.1 had a higher risk for CKD events compared to their counterparts with CAVI measurements <8.1, independently of cardiovascular risk factors. Participants with CAVI measurements ≥8.1 had a greater decline in annual eGFR compared to their counterparts with CAVI measurements <8.1.
year | journal | country | edition | language |
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2020-06-28 | American Journal of Hypertension |