6533b86dfe1ef96bd12c974f

RESEARCH PRODUCT

Falsely elevated intraocular pressure due to increased central corneal thickness

Philippe D’athisAlain M. BronSophie Goudeau-boutillonCatherine Creuzot-garcher

subject

AdultMaleIntraocular pressuremedicine.medical_specialtyprimary open-angle glaucomaAdolescentgenetic structuresEye diseaseOcular hypertensionGlaucomaCorneaCellular and Molecular NeurosciencePredictive Value of TestsCorneaOphthalmologyDiabetes mellitusHumansMedicineFalse Positive ReactionsProspective StudiesCorneal pachymetry[SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory OrgansProspective cohort studyAgedUltrasonographyAged 80 and overmedicine.diagnostic_testdiabetesbusiness.industryMiddle Agedmedicine.diseaseSensory Systemseye diseasesSurgeryOphthalmologymedicine.anatomical_structureocular hypertensionFemalecentral corneal thicknesssense organsbusinessGlaucoma Open-Angle[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyintraocular pressure

description

PURPOSE: To evaluate whether ocular hypertensive subjects have a higher central corneal thickness than other individuals. METHODS: In this prospective study, 48 subjects with ocular hypertension, 63 patients with open-angle glaucoma, 56 nonglaucomatous patients with diabetes mellitus, and 106 control subjects were evaluated. Corneal thickness was measured by ultrasound pachymetry, and intraocular pressure was determined by Goldmann applanation tonometry. RESULTS: Central corneal thickness was significantly higher in the ocular hypertensive subjects, mean +/- S.D., 592+/-39 microm, than in the patients with glaucoma (536+/-34 microm), the nonglaucomatous patients with diabetes mellitus (550+/-31 microm), and the normal subjects (545+/-33 microm), P0.05. CONCLUSION: In some individuals with increased transcorneal measurements of intraocular pressure, the cornea is thicker than in subjects with normal intraocular pressure readings or patients with glaucoma. It suggests that in ocular hypertensive subjects, corneal pachymetry should be performed to rule out an abnormally thick cornea as a reason for falsely high measurements of intraocular pressure.

yearjournalcountryeditionlanguage
1999-02-09
10.1007/s004170050222https://hal.inrae.fr/hal-02697101