6533b86dfe1ef96bd12c97d7
RESEARCH PRODUCT
BODIPY-phosphane as a versatile tool for easy access to new metal-based theranostics
Claire BernhardMichel PicquetAngela CasiniSemra TasanChristine GozeFranck DenatOlivier ZavaPierre D. HarveyBenoît BertrandPierre Le GendreEwen Bodiosubject
Boron Compoundsinorganic chemicalsCell SurvivalPhosphinesINHIBITIONchemistry.chemical_elementGOLD COMPOUNDSRutheniumInorganic ChemistryMetalchemistry.chemical_compoundGold CompoundsPOLYPYRIDINE COMPLEXESCoordination ComplexesCHEMISTRYCell Line TumorFluorescence microscopeHumansOrganic chemistryOsmiumCytotoxicityAGENTSMicroscopy ConfocalChemistryOsmiumCombinatorial chemistryRutheniumMetalsvisual_artPHOTOPHYSICAL PROPERTIESCancer cellvisual_art.visual_art_mediumMODESGoldBODIPYDYESBEHAVIORdescription
A new BODIPY-phosphane was synthesized and proved to be a versatile tool for imaging organometallic complexes. It also led to easy access to a new family of theranostics, featuring gold, ruthenium and osmium complexes. The compounds' cytotoxicity was tested on cancer cells, and their cell uptake was followed by fluorescence microscopy in vitro.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2012-12-13 |