6533b86dfe1ef96bd12c97dc

RESEARCH PRODUCT

Myeloid and T-Cell Microenvironment Immune Features Identify Two Prognostic Sub-Groups in High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms

Michele SimboloVincenzo LaganoMassimo MilioneValentina CrisafulliPaola SpaggiariGiovanni CentonzeSara PuscedduGiovanna SabellaNatalie PrinziGiovanna GarzoneTatiana BrambillaAlessandro MangognaAldo ScarpaBeatrice BelmonteAlessio PellegrinelliLaura CattaneoAndrea AnichiniMartina FilugelliClaudio Tripodo

subject

Oncologymedicine.medical_specialtyMyeloidmyeloid markersT cellCD3gastroenteropancreatic neuroendocrine neoplasms; myeloid markers; tumor microenvironmentCD33PopulationHuman leukocyte antigenSettore MED/08 - Anatomia PatologicaArticleSurgical pathology03 medical and health sciences0302 clinical medicineInternal medicinemedicinetumor microenvironmenteducation030304 developmental biologymyeloid marker0303 health sciencesTumor microenvironmenteducation.field_of_studybiologybusiness.industryRGeneral Medicinegastroenteropancreatic neuroendocrine neoplasms myeloid markers tumor microenvironmentgastroenteropancreatic neuroendocrine neoplasmsstomatognathic diseasesmedicine.anatomical_structure030220 oncology & carcinogenesisgastroenteropancreatic neuroendocrine neoplasmbiology.proteinMedicinebusiness

description

High-grade Gastroenteropancreatic Neuroendocrine neoplasms (H-NENs) comprehend well-differentiated tumors (NET G3) and poorly differentiated carcinomas (NEC) with proliferative activity indexes as mitotic count (MC) &gt

10.3390/jcm10081741http://hdl.handle.net/10447/510038