6533b86dfe1ef96bd12c97e3

RESEARCH PRODUCT

Decrease in Serum Vitamin D Level of Older Patients with Fatigue

E. M. ChisariGiuseppe LanzaManuela PennisiGiuseppe Di BartoloMichele MalaguarneraOmar CauliEnzo VicariGiulia MalaguarneraRita Bella

subject

Malesex differences0301 basic medicineVitaminmedicine.medical_specialtyAging; Mental fatigue; Older; Physical fatigue; Sex differences; Vitamin Dlcsh:TX341-641vitamin DHematocritGastroenterologyArticlevitamin D deficiencyCohort Studies03 medical and health scienceschemistry.chemical_compound0302 clinical medicineBlood serumInternal medicineolderVitamin D and neurologyHumansMedicineVitamin B12Mean corpuscular volumeFatigueAgedNutrition and Dieteticsmedicine.diagnostic_testbusiness.industryagingMiddle AgedVitamin D Deficiencymedicine.diseasemental fatiguephysical fatigue030104 developmental biologychemistryBlood chemistry030220 oncology & carcinogenesisFemalebusinesslcsh:Nutrition. Foods and food supplyFood Science

description

Fatigue is characterized by reduced energy level, decreased muscle strength, and a variable degree of cognitive impairment. Recent evidences seem to link vitamin D deficiency to fatigue. The aim of this study was to assess and compare vitamin D status in a cohort of older subjects with and without fatigue. We recruited a total of 480 subjects, 240 patients with fatigue and 240 controls without fatigue, from the Cannizzaro Hospital of Catania (Italy). Fatigue severity was measured by the fatigue severity scale, whereas mental and physical fatigue were measured through the Wessely and Powell fatigue scale, respectively. We also measured several blood parameters and 25-OH vitamin D. Subjects with fatigue showed lower levels of vitamin D as compared with those without fatigue. Blood levels of parameters related to fatigue were normal in both groups of subjects, however, platelet, hemoglobin, hematocrit (p &lt

yearjournalcountryeditionlanguage
2019-10-20Nutrients
https://doi.org/10.3390/nu11102531