6533b86dfe1ef96bd12c9e7b
RESEARCH PRODUCT
Die Wirkung von Theophyllin, Coffein und Theobromin auf Kontraktionskraft, Erregbarkeit, Refrakt�rzeit und Spontanfrequenz des isolierten Herzmuskels der Katze
G. KuschinskyErich Muschollsubject
PharmacologyInotropemedicine.medical_specialtyContraction (grammar)ChemistryRefractory periodGeneral Medicinechemistry.chemical_compoundmedicine.anatomical_structureEndocrinologyVentricleInternal medicinemedicineTheophyllineCaffeinePapillary muscleTheobrominemedicine.drugdescription
In the electrically driven papillary muscle of the cat's right ventricle theophylline, caffeine and theobromine exerted a positive inotropic action. Log. dose-effect regression lines for the three drugs were parallel; the effect of theophylline was significantly greater than those of caffeine and theobromine. The range of concentrations used was 1/32–1/2 mM/1.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1956-01-01 | Naunyn-Schmiedebergs Archiv f�r Experimentelle Pathologie und Pharmakologie |