6533b86dfe1ef96bd12c9e9b
RESEARCH PRODUCT
Unexpected metal-free synthesis of trifluoromethyl arenes via tandem coupling of dicyanoalkenes and conjugated fluorinated sulfinyl imines
Lia SotorríosCarlos Del PozoFernando López OrtizMaría Sánchez-rosellóAlvaro Sanz-vidalEnrique Gómez-bengoaDaniel Gaviñasubject
Reaction conditionsTrifluoromethylTandem010405 organic chemistryMetals and AlloysGeneral ChemistryConjugated system010402 general chemistry01 natural sciencesCombinatorial chemistryCatalysis0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic Materialschemistry.chemical_compoundMetal freechemistryMaterials ChemistryCeramics and Compositesdescription
A novel strategy for the synthesis of policyclic trifluoromethyl arenes has been devised. It involves a DBU-promoted tandem cycloaromatization reaction of dicyanoalkenes and fluorinated conjugated sulfinyl imines. This unprecedented transformation is a metal-free and air-tolerant process that takes place from readily available starting materials under mild reaction conditions.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2021-01-01 | Chemical Communications |