6533b86dfe1ef96bd12cab0d
RESEARCH PRODUCT
Demonstration of spotted fever group rickettsiae in the tache noire of a healthy person in Sicily.
David H. WalkerM. R. MontenegroSerafino MansuetoR. Di LeoG. TringaliM. Maniscalcosubject
MaleFluorescent Antibody TechniqueRickettsiaceae InfectionsTickBoutonneuse FeverVirologySkin UlcermedicineHumansRickettsiaSicilybiologyTache noir de la sclerotiqueMiddle Agedbacterial infections and mycosesmedicine.diseasebiology.organism_classificationRashVirologyAntibodies BacterialSpotted feverBoutonneuse feverTiterInfectious DiseasesRickettsiaImmunologybacteriaParasitologymedicine.symptomRickettsia conoriidescription
A human case of rickettsial infection occurred in Sicily following tick bite. The patient did not have fever, the typical nodular rash, or other symptoms of illness other than development of a tache noire containing spotted fever group rickettsiae, which were demonstrated by immunofluorescence. A high titer of antibodies of the IgG class suggests that the patient may have had previous exposure to Rickettsia conorii or a related spotted fever group rickettsia. An anamnestic response may be hypothesized to have conferred partial immunity, with resulting containment of rickettsiae at the site of inoculation.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1984-05-01 | The American journal of tropical medicine and hygiene |