6533b86dfe1ef96bd12cab52
RESEARCH PRODUCT
Long-Lasting Cranial Nerve III Palsy as a Presenting Feature of Chronic Inflammatory Demyelinating Polyneuropathy
Rossella SpataroVincenzo La Bellasubject
Diplopiamedicine.medical_specialtyWeaknessbusiness.industrylcsh:Rlcsh:MedicineCase ReportChronic inflammatory demyelinating polyneuropathyGeneral Medicinemedicine.diseaseNerve conduction velocitySurgeryCerebrospinal fluidPtosisSensationmedicineSettore MED/26 - Neurologiamedicine.symptombusinessPolyneuropathypolyneuropathy CIDP cranial nervesdescription
We describe a patient with chronic inflammatory demyelinating polyneuropathy (CIDP) in which an adduction deficit and ptosis in the left eye presented several years before the polyneuropathy. A 52-year-old man presented with a 14-year history of unremitting diplopia, adduction deficit, and ptosis in the left eye. At the age of 45 a mild bilateral foot drop and impaired sensation in the four limbs appeared, with these symptoms showing a progressive course. The diagnostic workup included EMG/ENG which demonstrated reduced conduction velocity with bilateral and symmetrical sensory and motor involvement. Cerebrospinal fluid studies revealed a cytoalbuminologic dissociation. A prolonged treatment with corticosteroids allowed a significant improvement of the limb weakness. Diplopia and ptosis remained unchanged. This unusual form of CIDP presented as a long-lasting isolated cranial nerve palsy. A diagnostic workup for CIDP should therefore be performed in those patients in which an isolated and unremitting cranial nerve palsy cannot be explained by common causes.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2015-04-01 | Case Reports in Medicine |