6533b86dfe1ef96bd12cab8b

RESEARCH PRODUCT

Local anesthetic switching for intrathecal tachyphylaxis in cancer patients with pain.

Patrizia FerreraPatrizia VillariSebastiano MercadanteEdoardo Arcuri

subject

AdultMalemedicine.medical_specialtyLung NeoplasmsLidocainemedicine.drug_classmedicine.medical_treatmentUterine Cervical NeoplasmsTachyphylaxisIntrathecalStomach NeoplasmsNeoplasmsmedicineHumansAnesthetics LocalCarcinoma Small CellTachyphylaxisBupivacaineChemotherapyLocal anestheticbusiness.industryPalliative CareCancerLidocaineMiddle Agedmedicine.diseaseBupivacaineSurgeryEndometrial NeoplasmsPain IntractableAnesthesiology and Pain MedicineAnesthesiaMorphineFemalebusinessmedicine.drug

description

IMPLICATIONS Switching from bupivacaine to lidocaine may improve intrathecal morphine analgesia in advanced cancer patients, possibly because of different spinal mechanisms limiting the hyperalgesic processes.

yearjournalcountryeditionlanguage
2003-07-01Anesthesia and analgesia
10.1213/01.ane.0000067403.15926.bdhttps://pubmed.ncbi.nlm.nih.gov/14742416