6533b86efe1ef96bd12cb2c4

RESEARCH PRODUCT

Sinusitis in Thyroid Associated Ophthalmopathy

W. J. MannG. KahalyS. DavrisHerbert Riechelmann

subject

Paranasal sinus mucosaModerate to severemedicine.medical_specialtybusiness.industryOrbital decompressionmedicine.diseaseGastroenterology03 medical and health sciences0302 clinical medicineOtorhinolaryngology030220 oncology & carcinogenesisInternal medicineotorhinolaryngologic diseasesmedicine030223 otorhinolaryngologySinusitisbusinessThyroid-Associated Ophthalmopathy

description

In 19 patients with thyroid associated ophthalmopathy undergoing orbital decompression, histologic examination of paranasal sinus mucosa revealed moderate to severe inflammatory alterations in all patients. Only 2/19 patients had a history of chronic sinusitis. In 4/19 patients, mucosal abnormalities of the paranasal sinuses were found on preoperative computed tomography CT scans. Postoperatively, 10/19 patients developed purulent sinusitis. It is suggested that patients suffering from thyroid associated ophthalmopathy have an increased incidence of histologically detectable inflammatory changes of paranasal sinus mucosa. Because of preexisting mucosal inflammation, these patients are prone to develop episodes of purulent sinusitis following endonasal orbital decompressions.

https://doi.org/10.2500/105065893781976285