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RESEARCH PRODUCT
Blue light mediated C–H arylation of heteroarenes using TiO2as an immobilized photocatalyst in a continuous-flow microreactor
David C. FabryThomas H. RehmWolgang TremelMagnus RuepingYee Ann HoMartin PanthöferRalf Zapfsubject
Materials science010405 organic chemistryContinuous flowSubstrate (chemistry)microreactor010402 general chemistryPhotochemistry7. Clean energy01 natural sciencesPollution0104 chemical sciencesCatalysischemistry.chemical_compoundchemistryddc:540Titanium dioxidePhotocatalysiscontinuous flowEnvironmental ChemistryIrradiationMicroreactorphotocatalysisBlue lightdescription
Titanium dioxide was applied as an immobilized photocatalyst in a microstructured falling film reactor for the continuous-flow C-H arylation of heteroarenes with aryldiazonium salts as the starting material. Detailed investigations of the catalyst and a successful long-term run proved its excellent usability for this process. Very good yields up to 99% were achieved with broad substrate scope and were compared with batch synthesis. The transfer to the continuous-flow mode revealed an impressive boost in reactor performance solely resulting from the improved irradiation and contact of the catalyst, substrate and light.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2017-01-01 | Green Chemistry |