6533b86efe1ef96bd12cb662

RESEARCH PRODUCT

Bacterial Biofilm Inhibition in the Development of Effective Anti-Virulence Strategy

Girolamo CirrincionePatrizia DianaStella CascioferroBarbara Parrino

subject

0301 basic medicinePharmacologyAntivirulenceChemistry030106 microbiologyBiofilm inhibitionPharmaceutical ScienceVirulenceantibiofilm antivirulenceMicrobiology03 medical and health sciences030104 developmental biologyDrug DiscoveryMolecular MedicineMedicinal Chemistry

description

There is an urgent need for new therapeutic strategies to counteract the global threat of antibiotic resistance, which has become, in recent years, one of the major public health concern. An important contribution to the microbial survival in hostile environments has been given by the capability of pathogens to form sessile communities able to adhere to biotic or abiotic surfaces, known as biofilms.

https://doi.org/10.2174/1874104501812010084