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RESEARCH PRODUCT
A New ZnIITweezer Pyridine-Naphthalene System - An Off-On-Off System Working in a Biological pH Window
Conxa SorianoJoão PinaM. Alexandra BernardoEnrique García-españaJavier AlarcónRicardo AucejoCarlos LodeiroFernando PinaJosé M. LlinaresJ. Sérgio Seixas De MeloKatherine L. Marchinsubject
Inorganic Chemistrychemistry.chemical_compoundAnthraceneFluorophoreQuenching (fluorescence)chemistryExcited statePyridineAmine gas treatingPhotochemistryFluorescencePhotoinduced electron transferdescription
Their basic idea consisted of the connec-tion of an amine to a fluorophoric anthracene unit on oneside and to a pyridine moiety on the other. At acidic pHvalues the amino and the pyridine groups are protonatedand a photoinduced electron transfer (PET) occurs fromthe π-π* excited state of the anthracene to the protonatedpyridinium unit, leading to quenching of the fluorescence.However, at high pH values, where the amino group is notprotonated, PET alternatively takes place from the aminelone pair to the same excited state of the fluorophore, yield-ing the same inhibitory effect on the fluorescence. Betweenthese two pH values, there is a pH window where PET doesnot take place and fluorescence emission is observed. Basedon this idea, A. P. de Silva et al. have developed several re-lated “off-on-off” fluorescent systems combining anthra-cene, pyridine and amino groups.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2005-10-24 |