6533b86efe1ef96bd12cca75

RESEARCH PRODUCT

Elaboration of Trans-Resveratrol Derivative-Loaded Superparamagnetic Iron Oxide Nanoparticles for Glioma Treatment

Dominique Vervandier-fasseurJulien BoudonLionel MauriziThomas NuryRihab HajiGérard LizardFadoua SallemNadine Millot

subject

Thermogravimetric analysisGeneral Chemical EngineeringNanoparticle02 engineering and technologyArticletrans-resveratrol derivativelcsh:Chemistry03 medical and health sciencesDynamic light scatteringX-ray photoelectron spectroscopygliomaZeta potentialMoleculeGeneral Materials Science[SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics030304 developmental biologyiron oxide superparamagnetic nanoparticles0303 health sciencesChemistry<i>trans</i>-resveratrol derivativefood and beverages021001 nanoscience & nanotechnology3. Good healthMembranelcsh:QD1-999Drug deliverydrug delivery0210 nano-technologyNuclear chemistry

description

In this work, new nanohybrids based on superparamagnetic iron oxide nanoparticles (SPIONs) were elaborated and discussed for the first time as nanovectors of a derivative molecule of trans-resveratrol (RSV), a natural antioxidant molecule, which can be useful for brain disease treatment. The derivative molecule was chemically synthesized (4&rsquo

10.3390/nano9020287https://www.mdpi.com/2079-4991/9/2/287