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RESEARCH PRODUCT

Celecoxib for recurrent sclerouveitis after syphilitic panuveitis. A case report

Ana M. SuelvesManuel Díaz-llopisSebastián Martínez-castilloMiguel Salavert

subject

musculoskeletal diseasesmedicine.medical_specialtygenetic structuresbusiness.industryBrief ReportPanuveitisSclerouveitisDermatologyeye diseasesOphthalmologyInfectious DiseasesCelecoxibBilateral syphilitic panuveitisCelecoxibmedicinelipids (amino acids peptides and proteins)heterocyclic compoundsTreponema pallidumskin and connective tissue diseasesbusinessOcular inflammationmedicine.drug

description

Purpose To report a case of recurrent ocular inflammation after optimal therapy of bilateral syphilitic panuveitis responding to oral celecoxib. Methods A case report was conducted. Results A 76-year-old man presented with painful blurry vision in both eyes. Ocular examination disclosed bilateral panuveitis. Serological testing confirmed blood and cerebrospinal fluid syphilitic involvement. After 2 weeks of intravenous penicillin therapy, recurrent episodic sclerouveitis was observed. Conclusion Ocular inflammation after healing of infectious uveitis is a rare ophthalmic sequela. In an immunocompetent patient, either re-infection or immune uveitis should be evoked. Non-steroidal therapeutic options, as celecoxib, could be a good option of treatment in such immune cases.

https://doi.org/10.1007/s12348-011-0031-0