A new electrophilic addition to acetylenes. Synthesis of 1,2-iodofunctionalized olefins

6533b86ffe1ef96bd12cdb54

RESEARCH PRODUCT

A new electrophilic addition to acetylenes. Synthesis of 1,2-iodofunctionalized olefins

José M. González José Barluenga Miguel A. Rodríguez Gregorio Asensio Pedro J. Campos

subject

Addition reaction Tetrafluoroborate Electrophilic addition Organic Chemistry Halocarbon Anisole Biochemistry Medicinal chemistry chemistry.chemical_compound chemistry Nucleophile Drug Discovery Pyridine Organic chemistry Aliphatic compound

description

Abstract Acetylenes react with bis(pyridine)iodo(I) tetrafluoroborate ( 1 ) in the presence of a wide variety of nucleophiles (F, Cl, Br, I, SCN, pyridine, OAc, anisole, H) to give 1,2-iodofunctionalized olefins ( 4 ).

year	journal	country	edition	language
1986-01-01	Tetrahedron Letters

https://doi.org/10.1016/s0040-4039(00)84782-6

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