Tuning inflammation in tuberculosis: the role of decoy receptors

6533b86ffe1ef96bd12cde5d

RESEARCH PRODUCT

Tuning inflammation in tuberculosis: the role of decoy receptors

Marco Pio La Manna Giuliana Guggino Francesco Dieli Serena Meraviglia Diana Di Liberto Alfredo Salerno Nadia Caccamo Guido Sireci

subject

Chemokine Decoy receptor medicine.medical_treatment Immunology Inflammation Mycobacterium tuberculosi Immunopathology Microbiology Mycobacterium tuberculosis Mice Immune system medicine Animals Humans Tuberculosis Decoy receptors Receptors Cytokine Receptor Cytokine Decoy receptors; TIR8/SIGIRR; D6; Mycobacterium tuberculosis; Cytokines; Chemokines; Immunopathology; Inflammation Inflammation Settore MED/04 - Patologia Generale Antiinfective agent biology Mycobacterium tuberculosis biology.organism_classification TIR8/SIGIRR Infectious Diseases Cytokine Chemokine Immunology biology.protein medicine.symptom D6

description

Decoy receptors are "silent scavengers" of CC chemokines and cytokines, which play a key role in damping inflammation and tissue damage. In this review we discuss on recent findings demonstrating that these receptors set the balance between antimicrobial resistance, immune activation and inflammatory response in Mycobacterium tuberculosis infection.

year	journal	country	edition	language
2009-01-01

10.1016/j.micinf.2009.05.004 http://hdl.handle.net/10447/46622

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