6533b86ffe1ef96bd12cdf6c

RESEARCH PRODUCT

An enantioselective synthesis of the C(33)–C(37) fragment of Amphotericin B

Kaisa KarisalmiAri M. P. KoskinenKari Rissanen

subject

Models MolecularAntifungal Agentsnatural productsFragment (computer graphics)ChemistryStereochemistryasymmetric synthesisOrganic ChemistryEnantioselective synthesisEstersStereoisomerismLigandsBiochemistryStreptomycesorganic chemistryModels ChemicalAmphotericin BAmphotericin BmedicinePhysical and Theoretical Chemistrymedicine.drug

description

An enantioselective synthesis of the C(33)–C(37) tripropionate fragment of Amphotericin B has been developed in only 6 steps. Peer reviewed

https://doi.org/10.1039/b305845j