6533b86ffe1ef96bd12ce432

RESEARCH PRODUCT

High resolution image in bone biology I : review of the literature

Jorge Cano SánchezJulián Campo TraperoJuan José VaqueroJosé María Martínez GonzálezAntonio Bascones Martínez

subject

UNESCO::CIENCIAS MÉDICAS:CIENCIAS MÉDICAS [UNESCO]

description

Bone microstructure has usually been assessed by obtaining samples invasively and analyzing them with conventional histomorphometric methods. Improvements in high-resolution image acquisition systems have enabled non-invasive assessment of bone morphology and a more precise 3-D evaluation by means of ?virtual biopsies?, permitting bone assessment in regeneration or remodeling processes. This review describes the characteristics and limitations of bone assessment using different high-resolution image systems (synchrotron-radiation computed tomography, micro-computed tomography, acoustic scanning microscope; micro-magnetic resonance imaging). Morphometric variables that can be obtained from these images are reported and compared with conventional histomorphometric variables.

http://hdl.handle.net/10550/63159