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RESEARCH PRODUCT
Metal complexes of sulfanilamide derivatives. Crystal structure of [Zn(sulfathiazole)2]·H2O
Gloria AlzuetJ. CasanovaJoaquín BorrásSantiago García-grandaEnrique Pérez-carreñoSacramento Ferrersubject
ChemistryStereochemistryCrystal structureCarbon-13 NMRBiochemistryInorganic ChemistryMetalCrystallographychemistry.chemical_compoundvisual_artProton NMRvisual_art.visual_art_mediumChelationThiazoleAntibacterial agentMonoclinic crystal systemdescription
Abstract The crystal structure of the Zn(sulfathiazole) 2 ·H 2 O complex is reported. The complex crystallizes in the monoclinic space group C 2/ c . The cell dimensions are a = 9.098(3) A, b = 17.871(5) A, c = 14.61(1) A, β = 99.44(6)°, V = 2343(2) A 3 , Z = 4, and D x = 1.68 g/cm 3 . The final conventional R-factor = 0.027 for 2669 “observed” reflections and 191 variables. The Zn ion is surrounded in a regular tetrahedral arrangement by two N amino and two N thiazole atoms pertaining to four sulfathiazole (Hstz) ligands. Each stz anion, acting as a bidentate ligand, chelates to two Zn ions as a bridge through the N thiazole and the N amino atoms. The IR, 13 C NMR in solid state, 1 H NMR, and 13 C NMR in DMSO d6 solutions spectra are discussed in detail with regard to the crystal structure.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1993-01-01 | Journal of Inorganic Biochemistry |