6533b86ffe1ef96bd12ce856
RESEARCH PRODUCT
Squaramide-based reagent for selective chromogenic sensing of Cu(II) through a zwitterion radical.
Jorge GonzálezCarmen RotgerElena SannaSalvador BlascoLuis A. MartinezAntonio CostaEnrique García-españasubject
Free RadicalsChemistryChromogenicOrganic ChemistrySquaramideElectron Spin Resonance SpectroscopyWaterHydrogen-Ion ConcentrationPhotochemistryBiochemistryAmideslaw.inventionchemistry.chemical_compoundlawZwitterionReagentChelationPhysical and Theoretical ChemistryNeutral phElectron paramagnetic resonanceOxidation-ReductionCopperCyclobutanesChelating Agentsdescription
A minimalist squaramide-based chemodosimeter for Cu(2+) is described. Upon selective chelation to 2, Cu(2+) induces the formation of a highly colored zwitterionic radical, which is kinetically stable for hours. The presence of a radical is confirmed by EPR and ESI-MS. It is then possible to use reagent 2 for visual and selective sensing of Cu(2+) at neutral pH.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2010-08-06 | Organic letters |