6533b870fe1ef96bd12cf2e6
RESEARCH PRODUCT
Performance of PSI, CURB-65, and SCAP scores in predicting the outcome of patients with community-acquired and healthcare-associated pneumonia
M FalconeS CorraoM VendittiP SerraG Licata For Simi Investigators IncludingRoberto Manfredinisubject
---medicine.medical_specialtySettore MED/09 - Medicina Internacommunity-acquired pneumoniaPneumonia severity indexBlood PressureSettore MED/10 - Malattie Dell'Apparato RespiratorioCommunity-acquired pneumonia Healthcare-associated pneumonia PSI CURB 65Severity of Illness IndexCommunity-acquired pneumoniaRespiratory RatePredictive Value of TestsInternal medicineCURB 65Severity of illnessInternal MedicinePneumonia BacterialMedicineHumansUreaPSIProspective StudiesIntensive care medicineProspective cohort studyConfusion---; community-acquired pneumonia; Healthcare-associated pneumonia; PSI; CURB 65Cross Infectioncommunity-acquired pneumonia; psi; healthcare-associated pneumonia; curb 65business.industryMortality ratemedicine.diseasePrognosisCURB-65Settore MED/45 - Scienze Infermieristiche Generali Cliniche E PediatricheHealthcare-associated pneumoniaCommunity-Acquired InfectionsPneumoniaCohortEmergency Medicinebusinessdescription
The objective was to compare three score systems, pneumonia severity index (PSI), the Confusion-Urea-Respiratory Rate-Blood pressure-65 (CURB-65), and severe community-acquired pneumonia (SCAP), for prediction of the outcomes in a cohort of patients with community-acquired (CAP) and healthcare-associated pneumonia (HCAP). Large multi-center, prospective, observational study was conducted in 55 hospitals. HCAP patients were included in the high classes of CURB-65, PSI and SCAP scores have a mortality rate higher than that of CAP patients. HCAP patients included in the low class of the three severity rules have a significantly higher incidence of adverse events, including development of septic shock, transfer into an ICU, and death (p < 0.01). At multivariate Cox regression analysis, inclusion in the severe classes of PSI, CURB-65, or SCAP scores and receipt of an empirical therapy not adherent to international guidelines prove to be risk factors independently associated with poor outcome. PSI, CURB-65, and SCAP score have a good performance in patients with CAP but are less useful in patients with HCAP, especially in patients classified in the low-risk classes.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2011-01-01 |